Medicine for the mind: How getting 40 winks can improve your mental health

Most of us would recognise that a lack of sleep on one day can affect our mood the next, making us grumpy, irritable, quick to lose our tempers and impulsive.

But a chronic lack of sleep can have a less well-acknowledged — and perhaps even more significant — impact on our mental health.

Sleep is when problems are solved and our memories are consolidated (‘imprinted’ on our brains). 

Poor sleep will destabilise brain function further and act to make the mental illness worse. And, of course, the symptoms of the mental illness will affect sleep. But if a lack of sleep is harmful to mental health, can improving sleep reduce the severity of mental illness? [File photo]

A lack of sleep will influence what we remember, and tired brains tend to remember our negative experiences, forgetting the positive ones. 

As I’ve explained before, this selective memory can lead to depression.

Indeed, insomnia is recognised as one of the most common features of mental illness, across depressive illnesses and psychosis, such as bipolar disorder and schizophrenia.

A deterioration in sleep can even be used as a predictor of mental health problems.

Until recently this link between a lack of sleep and mental illness was thought to arise largely as a side-effect of medication. 

This does not seem to be the whole story, as several studies have shown that people with mental illness can experience insomnia even when not taking medication such as anti-depressants or anti-psychotics.

Most of us would recognise that a lack of sleep on one day can affect our mood the next, making us grumpy, irritable, quick to lose our tempers and impulsive. But a chronic lack of sleep can have a less well-acknowledged — and perhaps even more significant — impact on our mental health [File photo]

Most of us would recognise that a lack of sleep on one day can affect our mood the next, making us grumpy, irritable, quick to lose our tempers and impulsive. But a chronic lack of sleep can have a less well-acknowledged — and perhaps even more significant — impact on our mental health [File photo]

So what is happening? It looks like there is an overlap between brain networks that govern our mental health and the brain circuits that generate sleep. 

As a result, any change in a brain circuit that causes mental illness will also affect sleep.

Poor sleep will destabilise brain function further and act to make the mental illness worse. And, of course, the symptoms of the mental illness will affect sleep. 

But if a lack of sleep is harmful to mental health, can improving sleep reduce the severity of mental illness?

This is an idea my team and I at Oxford decided to test, using cognitive behavioural therapy for insomnia (or CBTi), which, as I described in Wednesday’s Mail, is designed to change bad sleep habits and to encourage people to adopt behaviours that are proven to promote sleep — to treat insomnia without sleeping pills.

CBTi is available through a sleep clinic, or you can also do it yourself by using app-based digital CBTi, such as Sleepstation or Sleepio.

Sleep problems are notoriously common among care home residents. A Dutch study published in 2008 increased light in communal areas to about 2,000 lux and made bedrooms as dark as possible [File photo]

Sleep problems are notoriously common among care home residents. A Dutch study published in 2008 increased light in communal areas to about 2,000 lux and made bedrooms as dark as possible [File photo]

Our CBTi trial involved 3,755 people with insomnia as well as hallucinations and paranoia (a condition characterised by delusions of persecution, unwarranted jealousy or exaggerated self-importance).

A control group received no treatment for their insomnia; the rest received digital CBTi through an app on their smartphones.

Compared with the control group, those on digital CBTi experienced a significant reduction in insomnia — and a highly significant reduction in paranoia and hallucinations.

These exciting findings show that treatments for insomnia represent a new and powerful approach to reducing symptoms of mental illness. 

Improving older people’s mood 

CBTi approaches have been shown to help improve sleep and, as a result, help people lead healthier and happier lives. 

This is particularly true for older people, for whom CBTi, and light therapy, have improved sleep and health.

Did you know?

Boots pharmacies offer advice on sleep issues, with a number of sleep aid products available in store and an online quiz that can identify whether you have a problem. 

The Reboot quiz can be taken now at boots.com/reboot-quiz

In many nursing homes, light can be low, less than 200 lux in day areas and as little at 30 lux in TV rooms — this compares with between 10,000 to more than 60,000 lux outside, depending on the weather. Residents often see very little natural light.

Sleep problems are notoriously common among care home residents. A Dutch study published in 2008 increased light in communal areas to about 2,000 lux and made bedrooms as dark as possible. 

The residents’ sleep and wake patterns became more normal. They were waking less in the night, and had fewer daytime naps.

Significantly, improved sleep led to an increase in memory recall, problem solving, and feelings of wellbeing.

Using light intensity to help nursing home residents could be a cheap but effective alternative to drug treatments to calm night wanderers — and improve quality of life for patients. 

Employers must prioritise sleep 

Our understanding of sleep has grown greatly over the past ten years, and so has our awareness of the consequences of insomnia.

All this week I’ve looked at how, as individuals, we can take action to improve our sleep. 

Sleeping on it really can help solve your problems

The brain’s activity during sleep is highly complicated, with some areas of it being even more busy than when we are awake.

Our sleep occurs in cycles, moving through four recognised stages — the third and fourth stages are deep or slow-wave sleep, which is linked to memory and problem-solving.

Most slow-wave sleep takes place during the first half of the night. 

This may be the basis of the often-quoted saying ‘an hour of sleep before midnight is worth two hours of sleep after midnight’, though for what it’s worth, I think this is just a myth.

After 70 to 90 minutes, we move back from the deepest sleep into another state of sleep, rapid eye movement (REM), which is similar to the awake brain — the eyelids are shut, but the eyes move rapidly. 

Our heart rates and blood pressure increase, and the body is effectively paralysed from the neck down. This is when we have our most vivid dreams.

After some minutes of this sleep, there is a switch back to non-REM sleep.

The whole cycle then starts again. In an average night we may experience five of these sleep cycles. 

The problem with apps 

Sleep apps can help clarify when you went to sleep and woke up. 

However, some claim to measure the different stages of sleep, but this is very difficult — the readings you get may be misleading and could make you anxious.

Some apps claim to wake you in the morning when you are in REM sleep. 

We naturally wake from REM sleep, and the app calculates when you are in REM close to the time you have set your alarm.

While this is a great idea, the apps may have difficulty working out when you are in REM sleep. 

It is noteworthy that very few sleep apps have been endorsed by sleep academies or specialists. 

But employers can — and should — also take simple measures in the workplace to address problems arising from insomnia and night-shift work — for their benefit and that of their staff.

Employers and employees have to accept that there will always be significant health consequences associated with sleep loss, and that currently the best we can achieve is a reduction in the severity of symptoms associated with insomnia.

These are some of the changes that employers can make:

‘Drowsy driver’ alerts: Night-shift work and long working hours can reduce your ability to concentrate and lead to micro-sleeps (uncontrollably falling asleep). 

This can be dangerous both in the workplace and on the drive home, and it is worth emphasising that the tired brain is so impaired that it cannot detect how tired it is.

Driver insomnia has long been recognised as a major cause of road accidents. 

A recent UK study, for example, showed that 57 per cent of junior doctors had either had a vehicle crash or near-miss after working the night shift.

For many years, the rail industry has used some form of ‘dead man’s handle’, or driver safety device, built into locomotives to alert train drivers if they have lost vigilance or fallen asleep.

Such preventative measures have not been widely adopted in private cars or commercial vehicles — until recently.

A range of devices is now available, including steering- pattern monitoring, vehicle- position-in-lane monitoring, and driver eye/face monitoring to detect drowsiness.

Some motor manufacturers have recently incorporated this technology into newer models.

My own car is 14 years old and ready to be replaced, and the availability of such technology will influence the type of car that I will choose to buy next. 

It would be sensible and appropriate for employers to provide, or subsidise, such devices for staff.

Brighter lights: Increased tiredness and loss of vigilance during the night shift have been linked to an increased toll of accidents at work.

Keeping the office or factory sufficiently bright can improve alertness. 

To achieve peak alertness, a room should be lit with 1,000 lux or more.

Better food: Vending machines and canteens invariably supply sugary, fatty foods — just the kind of treats we seek when we’re tired, but which produce a sugar rush, followed by a crash and increased tiredness.

So don’t have a blow-out before you start work. 

The hidden health messages in dreams

You might be one of those people who ‘never’ dreams. But, in fact, we all do, every night — it’s just that some of us remember dreams better than others. 

This may be down to when we wake up in the sleep cycle.

Our most vivid, intense and bizarre dreams occur in rapid eye movement (REM) sleep — the period at the end of the 70 to 90-minute sleep cycle; this state of sleep is very similar to the awake brain.

We dream in both REM sleep and non-REM sleep, which makes up most of our night’s rest. But dreams in REM tend to be longer and more vivid. It’s unclear why.

We usually wake naturally from REM sleep so we may remember for a short time the last dream we experienced.

As for their content, dreams usually draw from our experiences — often recent ones — at some very basic level.

A current theory is that dreaming is a by-product of memory formation and problem solving — and REM sleep, particularly, is when we process emotional experiences that cause us stress when we are awake.

In this sense dreams may act as a ‘safety valve’ for a build-up of emotional worries. But we don’t really know.

However, there is no doubt that dreams can be linked to some medical conditions.

There is a group of sleep disorders, known as parasomnias, that involve unwanted experiences while you fall asleep, when you are sleeping or as you are waking up.

Parasomnias may include abnormal movements, behaviours, emotions, perceptions or dreams. 

They include so-called night terrors, which typically involve sitting up in bed and shouting, possibly lashing out.

Another parasomnia, REM sleep behaviour disorder, is where you act out vivid dreams during REM sleep.

Normally, the body is paralysed during this stage of sleep, but in this disorder the mechanism fails, so dreams are accompanied by lots of action and the dreamer may even be violent.

Devoted husbands have attacked and even killed their wives, mistaking their wife for an intruder during this dream state. 

The disorder has also been the basis for acquittals. However, it is not to be confused with sleepwalking, where the sleeper does not act out their dreams.

When woken from an episode of REM sleep behaviour disorder, the individual often recalls many details of the vivid dream.

The disorder is more common in people with certain conditions. It occurs in about 50 per cent of those with Parkinson’s, and is even as high as 95 per cent in some forms of dementia.

Parasomnias arise from altered brain circuitry. Some people are more likely to sleepwalk or have other parasomnias when they are feeling stressed.

Nightmares are a side-effect of some medications, so check the leaflet that comes with your prescription.

Ideally your canteen should help you by providing snacks and easy-to-digest foods, with lots of protein (to avoid sugar spikes).

Soups, nuts and seeds, boiled eggs, chicken and tuna are ideal. (I would love to see The Great British Bake Off have an episode dedicated to delicious recipes for night-shift workers!).

The right sleep type for the job: Our individual sleep needs are partly determined by our genes. 

Some people are ‘larks’ (get up and go to bed early, 14 per cent of the population), others are ‘owls’ (late-risers, late to bed, 21 per cent of the population) —and the rest of us are ‘intermediates’, or neutral types, meaning we broadly conform with the social norm in terms of sleep and wake times.

Studies have shown that the greater the mismatch between an individual’s chronotype — the propensity to sleep or be active at particular times — and the time they are required to work, the greater their risk of developing health problems such as type 2 diabetes.

Employers could chronotype their workforce with a simple questionnaire and then attempt to match chronotypes to specific work schedules.

In simple terms, the larks would be better suited to the morning shifts and the owls to the night shifts.

Clearly, this is not the complete solution, but it could go a long way towards reducing some of the problems of shift work.

Employers and employees have to accept that there will always be significant health consequences associated with sleep loss, and that currently the best we can achieve is a reduction in the severity of symptoms associated with insomnia [File photo]

Employers and employees have to accept that there will always be significant health consequences associated with sleep loss, and that currently the best we can achieve is a reduction in the severity of symptoms associated with insomnia [File photo]

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