News, Culture & Society

Sitting down could give you dementia

On Saturday, two eminent neurologists who specialise in Alzheimer’s told how their cutting-edge research has led them to believe lifestyle tweaks can help fend off the disease. Today, and in brilliant pullouts all this week, they share the personalised plan that could change your life . . .

The first flashes of forgetfulness often start in our 50s when we find ourselves grasping for a word just out of reach, or feel frustrated when trying to remember a close friend’s name.

We all worry that these ‘senior moments’ could be an early sign of dementia. With the condition now the number one cause of death in the UK, virtually every family is blighted by some form of the illness, which, until now, has had no effective treatment or cure.

But through decades of in-depth research and tireless work with elderly communities in California we are convinced that we have found a neurological solution more effective than any medication or pill.

Warning: Being inactive can have the same insidious effect as a poor diet, but regular movement and activity can be a tremendously powerful way to heal your brain and increase its strength

In Saturday’s Daily Mail, we introduced The Alzheimer’s Solution — a series of lifestyle changes powerful enough to prevent 90 per cent of Alzheimer’s cases, which can reverse debilitating symptoms and add happy, healthy years to all of our lives — which we write about in our book.

In yesterday’s paper, we highlighted the importance of diet. Our years of research have shown that decades of poor food choices harm the brain, but that switching to a brain-healthy diet can have an immediate brain-boosting effect.

Today, we will explain how being inactive can have the same insidious effect, but how regular movement and activity can be a tremendously powerful way to heal your brain and increase its strength.

Grow yourself a new brain

Our analysis of studies and years of work with people at varying stages of cognitive impairment have proved to us that exercising regularly boosts and optimises the brain’s immune system and increases the size of its most important memory structure.

It increases the manufacture of chemicals in the brain that strengthen the connections between the cells.


Prescribed blood pressure pills do their job by causing a precipitous drop in blood pressure, but they won’t, sadly, address any of the underlying problems that caused your symptoms in the first place.

If you don’t improve your lifestyle through a healthier diet, and especially by adding exercise into the mix, your cholesterol level will continue to build up, which will keep making your blood vessels even stiffer and narrower than before.

Eventually, you could get to the stage where you will require extra medication to widen the blood vessels, and if you still fail to address the lifestyle factors that elevate your blood pressure, you’ll reach the point where no amount of medication can maintain normal blood flow.

Exercise, in contrast to medication, not only helps pump blood to your brain, but also affects the underlying pathology that causes hypertension.

Regular exercise is even able to reverse damage by rejuvenating the blood vessels and increasing levels of the chemicals that help us grow new vessels. Exercise helps keep blood pressure balanced and naturally regulated — and that is really good news for your brain.

Exercise helps you maintain a healthy weight, cuts your risk of developing diabetes and even aids sleep. But, significantly, it reduces your chances of developing Alzheimer’s — and it takes almost immediate effect.

The problem is that so many of us now live completely without movement. We’re supposed to move a lot, not sit all day.

Many of our patients say they don’t know how to be active after so many years without exercise, especially when work and family commitments make prioritising exercise so hard.

But if, like many, you think you dislike exercise, let us tell you one thing for certain — you will hate Alzheimer’s far more.

Exercise doesn’t have to be a burden.

It can be simple, even enjoyable — and you don’t need much to make an impact.

Studies show that a daily brisk walk of just 15 minutes is enough to lower your risk of developing Alzheimer’s by 40 per cent.

Use the magazine which was given away in Saturday’s Daily Mail (if you haven’t got yours, call 0808 272 0808 and we’ll send you a copy) to help you personalise your exercise regime.

The charts will help you identify your strengths and limitations and ease yourself towards clear long-term activity goals.

You can’t just sit there

Before you pull on your trainers, sign up to a gym or nip out to buy a puncture repair kit for your bicycle, there are some small changes we urge you to make to inject lots more movement into your everyday life.

All the research agrees that there’s little worse for your brain’s long-term health than a sedentary desk-bound life topped off by an evening slumped in front of the TV.

Anything that reduces blood flow (such as long periods of inactivity) reduces brain function, especially in the areas of the brain that govern short-term memory.

Sedentary behaviour has been repeatedly associated with many chronic diseases, including cognitive impairment, and studies show the number of hours you spend sitting is proportional to your increased risk of Alzheimer’s.

What a healthy brain needs is movement throughout the day in short bursts, ideally every hour. So the factor to address first is the number of hours you spend sitting each day.

We now have standing desks in our office (standing up is much better for your brain than sitting) and a mini exercise machine that we jump on at intervals throughout the day.


Always  making excuses not to start exercising? Here’s why none of them will wash . . .

I’m too old: It can be tricky to find ways to get your heart beating fast when you have bad knees, sciatic disc problems or pain in your joints. Recumbent bikes, where you sit in a normal seat and pedal, mimic the motion of cycling but reduce pressure on the joints. If you have limitations with your legs, exercise your arms. You can also try less intense exercises such as yoga, tai chi or ballroom dancing.

I’m injured: Ask your GP for recommendations and focus on exercising uninjured areas.

I haven’t got time: Think about ways to modify your routine to include physical activity — take the stairs instead of the lift, for instance.

It’s raining: Wear appropriate clothes or exercise indoors.

I hate exercise: Combine your chosen exercise with something fun — music, audiobooks, podcasts, or get-togethers with friends.

If you are unwell or on medication, consult with your GP before starting any exercise programme. 

We nip out for a brisk walk most lunchtimes and we have frequent short breaks to do strengthening exercises such as press-ups and sit-ups. Now it’s completely normal for both of us to take one minute out of every hour and do as many sit-ups as possible.

At home in our living room we have a stationary bike which we use when watching TV in the evening, a set of weights and resistance bands, a mat, a small step stool (for step-ups) and enough space for press-ups and sit-ups.

You don’t need any of this equipment to get started, but you do need to do whatever it takes to incorporate more movement into your day and reduce the stagnating time spent sitting.

Aim to get into the habit of standing up to take any phone call, or, better still, walk and talk. When friends suggest meeting for coffee, suggest a walk, instead. If the weather is bad, window shopping at a large covered shopping centre works just as well.

Stop using the car for short trips, do a few sit-ups before getting out of bed and squats when you are brushing your teeth. Research has shown that leg strength in particular is linked with better cognitive function, possibly because strong legs help blood circulate up to the brain.

So, just regularly working to strengthen the legs with a few partial squats while holding on to a chair is enough to have a significant positive effect on the brain.

If you have an exercise bike, drag it out of the garage and position it in front of the TV, or pick up a mini pedal exerciser (available online for about £20) to use under your desk, or in place of your footstool so you can get your legs going round when you’d be otherwise inactive.

Set an alert on your phone to ping every hour to remind you to run through a series of simple squats (stand up from your chair and lower yourself repeatedly so your bottom almost touches the chair before standing again), stretches, or press-ups against the wall.

This might call for a bit of creative thinking about the way you work, but it is worth investigating the possibility of a standing desk.


The key to a successful exercise plan is making it:

Manageable: Start at a pace and time slightly higher than what you think you can do, and increase by weekly increments.

Convenient: Bring your exercise bike into the sitting room, hide the TV remote, wear trainers to work.

Repeatable: Make sure the activities are easy, efficient and enjoyable.

Incremental: Aim for one more squat a day, for instance.

Measurable: Track your progress. Use Saturday’s workbook or a smartphone app. 

Take the stairs rather than the lift at every possible opportunity, never sit when you can stand, never stand when you can walk, or walk slowly when you can swing your arms and walk quickly. Now, you’re ready to add proper exercise into the brain-boosting mix.

Take it up a notch

Any form of activity that gets your heart pumping is great for the brain.

As we age, we lose brain cells and the connections between them weaken and fail. A lot of evidence, however, shows that aerobic exercise (which raises your heart rate) can enhance connectivity throughout the brain, improve thinking power and protect against dementia in general and Alzheimer’s in particular.

Aerobic activity seems to boost not just the number of connections, but the strength and connectivity of each of them, and is crucial if you are going to be able to recall memories as you get older. If too many connections fail, you’ll lose your cherished memories for ever.

We now know that the brain can continue to grow into middle and even older age and exercise appears to be the most significant lifestyle factor when it comes to generating new cells in the brain. Studies show that any movement — even fidgeting — triggers the synthesis of chemicals which act like fertiliser for the brain cells.

Having strong muscles, and using weights or adding a little bit of resistance training should, ideally, form part of your exercise mix, too.


 Everything we know about the brain suggests that complex activities provide the best protection against cognitive decline. Netball or basketball won’t just get the blood pumping, they’ll strengthen your reflexes, balance and co- ordination and challenge your brain.

Yoga involves awareness of muscle groups and challenges balance, breathing and attention.

Even playing on a Nintendo Wii offers a constantly changing interface that keeps the brain engaged and can be a great alternative for those who get bored with bikes and treadmills. 

Studies show weight training improves reasoning and attention skills and stops the formation of cholesterol plaques, thereby increasing the supply of essential nutrients to the brain.

Whatever you choose to do, the important issue, for the sake of your brain, is to do something.

It is too easy to make excuses and wriggle out of exercise, but protecting your brain against Alzheimer’s requires exercise to be a priority. Commit to doing some form of movement every day. It doesn’t matter if you’re walking, jogging, cycling, dancing, swimming, nipping up and down the stairs, doing star jumps or repeatedly stepping on and off your bottom step.

If you really don’t feel in the mood, start doing something anyway, and do it for at least five minutes. Any exercise is better than none.

We have found with our patients that the best results occur when activity, movement and exercise become completely habitual and intertwined with your daily life.

  • Adapted from The Alzheimer’s Solution: A Revolutionary Guide To How You Can Prevent And Reverse Memory Loss by Dr Dean Sherzai and Dr Ayesha Sherzai, published by Simon & Schuster on October 5 at £14.99. Order a copy for £10.49 (valid until October 7, 2017) at or call 0844 571 0640. Free P&P on orders over £15.


For a great way to get started with your new activity programme, try these basic exercises you can do in your living room:

Better balance

Choose one of these balance exercises and do it every day. Before your balance improves, or if you don’t feel too steady, you can do them with a chair next to you for extra support in case you need it.

Heel-to-toe walk: Walk in a straight line, placing the heel of one foot directly in front of the toes of the other foot — don’t look at your feet.

Single leg balance: Raise one leg, bringing the knee forwards and up, and hold for 10-12 seconds. Lower and switch legs.

Back leg raises: Raise one leg, pushing the knee backwards and up, and hold for 10-12 seconds. Lower and switch legs.

Side leg raises: Raise one leg, extending it sideways, and hold for 10-12 seconds. Lower and switch legs.

Tree pose: Stand with your back to the wall and lift one leg, resting your foot above or below the knee of the standing leg. Lift your arms in the air. As your balance improves try stepping away from the wall and closing your eyes while doing it.

Flexibility Training

Stretching or flexibility exercises are an important part of any physical activity programme and an important step to protect you from injury.

First, warm up with a few minutes of gentle walking. Then hold each stretch for 10-30 seconds. Repeat each one 3-5 times.

Do these stretches at regular intervals throughout the day:

Neck stretch: Tilt your head side to side and front to back. Follow with gentle neck circles.

Shoulder and back stretch: Interlace your fingers and raise your arms above your head with your palms facing the ceiling. Extend your elbows and press your arms upwards.

Shoulder rotator stretch: Bend your right elbow and place your arm behind your back with your palm facing away from you.

Holding a towel with your left hand, extend that arm over the back of your head. Slowly bend your left elbow, bringing your left hand towards your right hand. Take hold of both ends of the towel firmly.

As you breathe you may be able to bring the hands closer to each other, increasing the stretch.

Wrist stretch: Rotate the wrists in circles, both clockwise and anticlockwise. Extend your arm and use your opposite hand to stretch your fingers both upwards and downwards.

Lower back stretch: Sit on the ground with your back upright and your legs extended straight in front of you .

Slowly hinge at the waist and reach for your toes.

Over time your head will get closer to your knees.

Hip stretch: Stand upright. Circle your hips in each direction. Then, extend your torso to each side, lengthening your waist.

Hamstring stretch: Stand upright. Bend at your waist, lengthening your torso over the fronts of your thighs, reaching down with your arms towards your toes.

You may need to bend your knees at first, but work towards straightening your legs.

Knee stretch: Circle your knees in each direction. Gently bend and straighten.

Ankle stretch: Rotate your ankles in each direction. While seated, use your hand to stretch your foot upwards, downwards and to the left and right.

Clever tricks to boost your memory

To effectively exercise your short-term memory, you should aim to use emotional links, association and repetition. The more senses you involve while you memorise things, the better.

Stories are also integral to memory and linking them can be a powerful tool in building memory. Read the list below once, cover the newspaper, and jot down as many items you can remember.

Then try the techniques below, which instantly boost your ability to memorise . . . read the list once more, and do the task again.








Office Supplies:

Sticky tape


Sticky notes


Cleaning Supplies:

Air freshener


Washing-up liquid

Laundry whitener


 Kitchen paper

Scented multi- surface cleaner

Window cleaner

Kitchen Items:

Chopping board

Olive oil




This powerful exercise combines four different thought processes to create memorable scenes which enhance memory. It’s quite simple — just remember ACES and make the game as silly and emotional as you can (it helps build your brain power):

Attention. Pay attention to the piece of information or word you’re trying to remember.

Connect. Associate that information with other related things using something that will make the information distinctive.

Emotion. Create an emotional link to the information.

Senses. Try to associate other senses with the information (images, smells, tastes, etc).

Let’s say you’re trying to memorise the words ‘apple’ and ‘peacock’. Here’s an example of how to use ACES:


Attention: Visualise an apple.

Connect: Think of Snow White biting the poisoned apple.

Emotion: Feel the dread as she takes a bite.

Senses: See the apple’s colour (deep red), hear the crunch, taste the sweetness and say ‘apple’.


Attention: Visualise the peacock.

Connect: Think of Sleeping Beauty surrounded by peacocks.

Emotion: Suddenly the peacocks start flying all around her.

Senses: See the peacocks’ vibrant green feathers, touch their elaborate tails, hear them chirping and say ‘peacock’.


This strategy uses a familiar room to help you memorise a list of items — let’s say you choose your bedroom: as you enter, you see a bed with four pillows, a table, a floor lamp and a large window. When you’re memorising a list, simply associate each item with an object or place in your bedroom.

For example: You enter the room to a strong scent of a scented multi-surface cleaner.

Your bed is in front of you, and you notice that your bedding is glaringly white because you used laundry whitener to wash it.


Choose a specific object that you see regularly — your favorite necklace or painting perhaps — and imagine it in great detail. See all aspects of the object. Hold all those thoughts in your head, maintaining your focus on that object for at least three minutes. 

You look to the left and see the lamp, but it’s actually a broom.

The lampshade is made of a giant banana peel!

Then you look at the window and see a sticky note tacked on to the window with sticky tape.


We have a limited capacity to memorise a list but ‘chunking’ items by category or association can make things more effective.

Try ‘chunking’ the list above into four categories: six types of fruit, four office supplies, seven cleaning supplies and four kitchen items.

Labelling these chunks as 6F, 4O, 7C and 4K will make them even more memorable.

Or try associating each item with a story that involves familiar people and settings.For example:

Sticky tape: Mary is known for being organised, so imagine as you enter a room she is taping a large ‘to do’ list on the wall.

Pencils: Mary grabs a pencil and adds another task to her list.

Sticky notes: Mary writes on sticky notes and adds them to her list — she’s almost run out of room.

Stapler: Mary staples another page on to the original list and continues planning her day.

Quick-fix brain boosting meals

Spiced bean stew

(Serves 2)

● Splash of olive oil

● 50 g finely diced chorizo (optional)

● 1 small onion, sliced

● 1 garlic clove, chopped

● 1 heaped tsp paprika

● 1 pinch of chilli flakes

● 1 tin of tomatoes

● 200 ml vegetable stock

● Salt & pepper

● 1 tin of cannellini beans, drained

● 50 g greens (chopped spinach, kale, courgettes)

● Juice of ½ a lemon

● 15 g flat leaf parsley, chopped

Heat the olive oil in a pan and fry the chorizo (if using) on a high heat for 2-3 minutes, stirring regularly.

Turn the heat down and add chopped onion. Saute over a low heat for 10 minutes until soft. Add garlic, paprika and chilli flakes and cook for a further 2 minutes, stirring regularly. Add the tinned tomatoes and vegetable stock and season. Let this simmer for 10 minutes to let the flavours develop and create a sauce.

Add the beans and cook for 5 minutes, before adding the greens, lemon and parsley. Put the lid on, let the greens wilt for a couple of minutes and serve.

One pot pasta with anchovies and spinach 

(Serves 2)

● 200g wholewheat spaghetti

● 200g cherry tomatoes, halved

● 6 anchovy fillets, finely chopped

● 2 cloves of garlic, chopped

● 50ml olive oil

● 200g spinach (or leftover veg)

● Juice of 1 lemon

● Salt & pepper

Place spaghetti, tomatoes, anchovies, garlic and oil into a large pan and season.

Pour over 600 ml of boiling water, put the lid on and bring to the boil.

Simmer for 10 minutes, stirring regularly and adding more water if it looks like it is drying out. The pasta cooks in the water with the other ingredients and makes its own sauce.

When the pasta is nearly cooked, throw in the spinach and squeeze in lemon juice, cover and cook for a further 2-3 minutes. Serve with an extra drizzle of olive oil. Add chilli, olives or capers to taste.

Asian brown rice broth

(Serves 2)

● Drizzle of olive oil

● 5 spring onions, sliced

● ½ red chilli, chopped

● 1 chopped garlic clove

● 1 tsp ground ginger

● 1 heaped tbsp miso paste

● 800ml veg stock

● 2 star anise

● 200g mixed vegetables, sliced

● 75g cooked brown rice

● Juice of 1 lime

Heat oil in a saucepan over a low heat and saute spring onions, chilli and garlic for 5 minutes until soft.

Add ground ginger and miso paste and briefly mix over the heat.

Pour in vegetable stock and add star anise.

Bring to the boil and simmer for 10 minutes to allow the flavours to infuse. Add vegetables and cook for 2-3 minutes or until cooked through. Add rice, soy sauce and lime juice and stir well.

Sweetcorn, spinach and quinoa fritters

(Serves 2)

● 100g spinach

● 75g cooked quinoa

● 150g sweetcorn

● 1 egg white

● 2 tbsp plain flour

● ½ tsp baking powder

● Salt & pepper

● Pinch of chilli flakes

● 1 tbsp olive oil

Steam and drain the spinach, roughly chop it and set aside.

Mix quinoa, sweetcorn, egg, flour, baking powder, salt, pepper and chilli in a bowl. Add chopped spinach and mix again. Heat olive oil in a frying pan and spoon the mixture into the pan (this mix will make 4 good-sized fritters). Fry each side for 2-3 minutes until golden brown.

Serve with a big green salad.