Stopping exercise worsens depression in as little as three days

Stopping exercise can worsen depression in as little as three days, new research suggests. 

In a review of six studies assessing the impact of ceasing activity in sufferers of the mental-health condition, results imply their symptoms, such as a continuous low mood, appear almost immediately.  

Study author Professor Bernhard Baune, from the University of Adelaide, said: ‘It is important that people understand the potential impact on their mental wellbeing when they suddenly cease regular exercise.’

PhD student Julie Morgan, who was also involved in the study, added: ‘At least 150 minutes of moderate intensity exercise a week is recommended to maintain health and prevent depression or 75 minutes of vigorous intensity exercise for added health benefits.’

Previous research suggests being active increases the release of feel-good endorphins, which boost people’s moods and promote calmness.

Around three per cent of adults in the UK suffer from depression every year. 

Stopping exercise can worsen depression in as little as three days, research suggests (stock)

DOES EXERCISE PREVENT DEMENTIA?

Aerobic exercise such as walking and running may halt dementia by preventing the brain from shrinking, research suggested in November 2017.

Being active several times a week maintains the size of the region of the brain associated with memory, a study found.

Known as the hippocampus, this region is often one of the first to deteriorate in Alzheimer’s patients.

Lead author Joseph Firth from the Western Sydney University, said: ‘When you exercise you produce a chemical called brain-derived neurotrophic factor (BDNF), which may help to prevent age-related decline by reducing the deterioration of the brain.

‘In other words, exercise can be seen as a maintenance programme for the brain.’

The scientists, from the universities of Western Sydney and Manchester, analysed 14 studies with a total of 737 participants.

The participants were aged between 24 and 76, with an average age of 66.

They were made up of healthy individuals, Alzheimer’s patients and people with mental health problems, such as depression and schizophrenia.

Scans of the participants’ brains were investigated before and after completing exercise, such as walking or treadmill running.

The exercise programmes lasted between three months and two years, with participants completing two to five sessions a week.  

Symptoms appear in just three days   

Speaking of the findings, Professor Baune said: ‘In some cases, ceasing this amount of exercise induced significant increases in depressive symptoms after just three days.

‘Other studies showed that people’s depressive symptoms increased after the first one or two weeks, which is still quite soon after stopping their exercise.’

He adds, however, the number of patients analysed was fairly small and therefore the experiment should be repeated, particularly as there is relatively little research investigating the effect of exercise on depression.

Results further suggest female depression sufferers are more likely to experience such symptoms after stopping exercise than males. 

Symptoms also quickly appear even if other signs of the mental-health condition, such as inflammation, are not present.  

How the research was carried out   

The researchers analysed studies investigating the link between stopping exercise and depressive symptoms.

In total, 152 otherwise healthy adults were assessed. 

The findings were published in the Journal of Affective Disorders. 

Depression increases the risk of premature death 

This comes after research released in October last year suggested depression increases the risk of an early death by up to three times.

Men’s risk of a premature passing increases three-fold when suffering from the mental-health condition, while women’s risk is heightened by up to 51 per cent.

Previous research suggests depression causes the release of stress hormones that suppress the immune system, putting sufferers at an increased risk of conditions such as cancer.

People with the mental-health disorder may also be more likely to have unhealthy lifestyle habits, including a poor diet, inactivity and excessive alcohol intake, past studies imply.

Lead author Stephen Gilman from the Eunice Kennedy Shriver National Institute of Child Health and Human Development in Maryland, said: ‘For some individuals depression can be very serious condition.

‘It is very important to seek treatment for depression and to be vigilant about recurrences.’ 



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