Cannabis users are more likely to experience negative emotions, particularly feeling alienated from others, research suggested in January 2018.
People who use marijuana are significantly more likely to feel that others wish them harm or are deceiving them, a study found.
Brain scans also reveal the class-B drug increases signal connectivity in regions of the brain that have previously been linked to psychosis, the research adds, which is associated with severe depression.
Teenage cannabis users are particularly affected as their brains are still developing, according to the researchers from the National Institute on Alcoholism and Alcohol Abuse in Bethesda.
The scientists analyzed 60 people, half of which were cannabis dependent.
The study’s participants completed a questionnaire that asked them about their feelings of stress, aggression, reactivity and alienation.
Brain scans were also taken of all of the participants.
In the US, 44 percent of those aged 12 or over have used cannabis at some point in their lives.
Around 2.1 million adults in the UK use marijuana every year.