The FDA-approved food ingredient -caryophyllene can activate the endocannabinoid system.
Many plants, perfumes, preservatives, additives, and flavoring compounds all contain it. Cannabinoid receptor type 1 (CB1) and CB2 receptors make up the endocannabinoid system.
Endocannabinoids including THC and CBD, as well as arachidonic acid, bind nonselectively to both CB1 and CB2 receptors.
Cannabis (marijuana) has psycho modulatory effects due to CB1 receptors, whereas CB2 receptors are effective in treating inflammation, pain, atherosclerosis, and osteoporosis.
Beta-caryophyllene terpenes bind strongly to CB2 receptors and activate many of the endocannabinoid system’s effects.
Beta-Caryophyllene Terpenes Benefits You Should Be Getting
Helps to Prevent Diabetes. High doses of Beta-caryophyllene (used orally) may help lower blood sugar levels. Beta-caryophyllene, for example, has been shown to balance glucose levels in diabetic rats, similar to the anti-diabetic medication glibenclamide.
By protecting pancreatic beta-cells from hyperglycemia and improving insulin/glucose signaling, Beta-caryophyllene may be able to prevent the development of insulin resistance.
Relieves Pain. Beta-caryophyllene can enhance natural endorphins and reduce inflammation by targeting the opioid and endocannabinoid systems. It can also be used topically and locally in painful locations.
Beta-caryophyllene can aid in the reduction of muscle spasms and pain.
Can Help Prevent Cancer. Beta-caryophyllene may aid in the prevention of cancer. Beta-caryophyllene, for example, inhibited tumor growth in mice fed a high-fat diet in animal research. If Beta-caryophyllene is oxidized, its anti-cancer actions may be enhanced.
By decreasing PI3K, AKT, mTOR, and S6K1 and boosting MAPK, oxidized Beta-caryophyllene (CPO) can decrease cancer cell proliferation and cause apoptosis (self-destruction).
Affect on Sex Organs. Endometriosis is a condition in which tissue grows abnormally outside the uterine lining. Beta-caryophyllene has been found in animal tests to relieve endometriosis symptoms without impacting fertility.
Beta-caryophyllene may operate as a male contraceptive by reducing sperm viability and sperm count in male mice, according to research (but not decreasing overall sperm production).
Treatment of Alcoholism. Beta-caryophyllene may be beneficial in the treatment of alcoholism. Beta-caryophyllene treatment, for example, reduced the mice’s dependence on alcohol in a research where they were addicted to it.
Alzheimer’s Disease Prevention. Beta-caryophyllene may aid in the prevention of Alzheimer’s disease (AD).
Beta-caryophyllene can diminish amyloid-beta plaques and immune-induced inflammation in the brain by activating CB2 receptors and upregulating PPAR-gamma, therefore preventing cognitive impairment.
Parkinson’s Disease: It Might Help. Dopamine deficiency and oxidative stress are characteristics of Parkinson’s disease (PD). Beta-caryophyllene inhibits dopamine loss and oxidative stress in the brain via activating CB2 receptors.
Protects The Gastrointestinal Tract. Inflammatory Bowel Diseases may benefit from Beta-caryophyllene.
Beta-caryophyllene, for example, can lower colon inflammation by activating the CB2 and PPAR-gamma receptors. When coupled with Curcumin, EGCG, or Baicalin, these anti-inflammatory properties can be amplified.
Help To Lower Cardiac Tension. Beta-caryophyllene protects the brain by reducing neuroinflammation (brain inflammation) and increasing antioxidant levels.
Beta-caryophyllene, for example, can raise glutathione levels via activating the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) pathway, which can protect against glutamate-induced oxidative damage.
Lightens The Skin. Beta-caryophyllene can reduce melanin synthesis and may help with skin-whitening.
The Vascular System Is Protected. Beta-caryophyllene can aid in Vascular Dementia by improving blood flow to the brain (VD). Beta-caryophyllene can also help to lower cholesterol levels (hypercholesterolemia).
Some More Beta-Caryophyllene Terpenes
- Protects the kidneys
- May improve bone density
- Improve weight loss
- Helps with sleep
- May improve oral hygiene
- May improve stroke outcome
- May increase longevity and mitochondrial function
Bottomline
Caryophyllene is unique in that it can directly activate cannabinoid receptors, particularly CB2.
It’s also recognized for causing some relaxation and for being able to successfully calm anxious behavior.
This unique terpene oil can be found in a variety of foods, including cinnamon, cloves, rosemary, hops, and black pepper. When talking about its presence in cannabis strains, it has a characteristic, spicy, warm, peppery flavor and aroma, with notes of gas or gasoline.
Beta-caryophyllene has the potential to improve one’s health, but additional research is needed.
Use Nuturawellness’s products to get your daily dose of terpenes
To give you the finest daily dose of terpenes possible, Nutura’s hemp products are made entirely of natural organic ingredients.
At Nuturawellness handpick the highest-quality, chemical-free Australian hemp oil from across the world to manufacture the best-selling CBD cosmetics and edibles. At Nuturawellness make it a point to provide their clients with the most nutrient-dense, long-lasting foods possible.