Declining sperm counts and doubling rates of testicular cancer could be a ticking time bomb for the human race, a leading scientist claims.
Sperm counts have halved in the western world over the past four decades, which, alongside rising testicular tumours, could be behind plummeting fertility rates and couples’ increasing dependency on IVF, according to Professor Niels Skakkebaek from the University of Copenhagen.
Hormone-disrupting pesticides sprayed onto everyday food may be too blame as the changes are occurring too rapidly for genetics to be at fault, he adds.
Professor Skakkebaek said: ‘Alterations in our genome cannot explain the observations as changes have occurred over just a couple of generations.
‘Modern lifestyles are associated with increased exposure to various endocrine-disrupting chemicals such as pesticides that may be harmful to humans even though exposure to individual chemicals is low.’
Declining sperm counts could be a ticking time bomb for the human race, scientists claims
‘Pesticides may be harmful to humans’
Professor Skakkebaek said: ‘What could be causing such disturbing trends? The short answer is that we do not know.
‘However, data suggesting that the incidence of testicular cancer has more than doubled in recent decades leaves little doubt that we should look into environmental causes, including lifestyle effects.
‘Alterations in our genome cannot explain the observations as changes have occurred over just a couple of generations.
‘Environmental exposures can come through food, water, skin, and work and home environments.
He said: ‘Both wildlife research and experimental studies suggest that modern lifestyles are associated with increased exposure to various endocrine-disrupting chemicals such as pesticides that together may be harmful to wildlife and humans even though exposure to individual chemicals is low.
‘However, little has been done to explore their potential effects on semen quality and testicular cancer.’
‘We have already waited too long’
Professor Skakkebaek said: ‘In particular, studies of maternal exposures in pregnancy and the subsequent reproductive function of their sons are needed.
‘Should we be worried about our future ability to reproduce ourselves, as some media coverage has claimed?
‘This inconvenient question makes sense when we look at what is going on in fertility clinics all over the world – more and more children are now born after in vitro fertilisation, intracytoplasmic sperm injection and insemination with partner or donor sperm.’
‘Simple research questions urgently need answers.
He added: ‘What is the role of exposure to endocrine disrupting chemicals in reproductive trends? What is the role of lifestyle factors, including recreational drugs?
‘Why is the incidence of testicular cancer increasing among young men of reproductive age?
‘We have already waited too long. ‘
Professor Skakkebaek’s comments appear in the British Medical Journal.