The Centenary Copa America kicks off with hosts USA taking on Colombia at the Levi’s Stadium in Santa Clara, California.
Elsewhere Argentina kick-off their campaign in Group D in a repeat of last year’s final against Chile at the same venue on June 7, while Brazil take on Ecuador in their Group B opener against Ecuador at the Rose Bowl in Pasadena, California.
Here, Sportsmail gives you the definitive guide to the dates, schedule, times and locations of each match from the tournament in the US.
ALL TIMES BST
James Rodriguez’s Colombia take on USA in the tournament opener at 2am BST in Santa Clara, California
GROUP A
USA v Colombia, June 4, Santa Clara, CA, 2.30am
Costa Rica v Paraguay, June 4, Orlando, FL 10pm
USA v Costa Rica, June 8, Chicago, IL, 1am
Colombia v Paraguay, June 8, Pasadena, CA, 3.30am
USA v Paraguay, June 12, Philadelphia, PA, 12am
Colombia v Costa Rica, June 12, Houston, TX, 2am
Costa Rica’s Keylor Navas will come up against Real Madrid team-mate Rodriguez on June 12 in Houston
GROUP B
Haiti v Peru, June 5, Seattle, WA, 12.30am
Brazil v Ecuador, June 5, Pasadena, CA, 3am
Brazil v Haiti, June 9, Orlando, FL, 12.30am
Ecuador v Peru, June 9, Glendale, AZ, 2am
Ecuador v Haiti, June 12, East Rutherford, NJ, 11.30pm
Brazil v Peru, June 13, Foxborough, MA, 1.30am
Chelsea midfielder Willian will be in action for Brazil when they kick off their tournament against Ecuador
GROUP C
Jamaica v Venezuela, June 5, Chicago, IL, 10pm
Mexico v Uruguay, June 6, Glendale, AZ, 12am
Uruguay v Venezuela, June 10, Philadelphia, PA, 12.30am
Mexico v Jamaica, June 10, Pasadena, CA, 3am
Mexico v Venezuela, June 14, Houston, TX, 1am
Uruguay v Jamaica, June 14, Santa Clara, CA, 3am
Luis Suarez will come up against Leicester captain Wes Morgan when Uruguay play Jamaica on June 14
GROUP D
Panama v Bolivia, June 7, Orlando, FL, 12am
Argentina v Chile, June 7, Santa Clara, CA, 3am
Chile v Bolivia, June 11, Foxborough, MA, 12am
Argentina v Panama, June 11, Chicago, IL, 2.30am
Chile v Panama, June 15, Philadelphia, PA, 1am
Argentina v Bolivia, June 15, Seattle, WA, 3am
Lionel Messi’s Argentina face Chile in a repeat of last year’s Copa America final in the Levi’s Stadium, June 7
QUARTER-FINALS
Winner A v Runner-up B (June 17, Seattle, WA, 2.30am)
Runner-up A v Winner B (June 18, East Rutherford, NJ, 1am)
Winner C v Runner-up D (June 19, Santa Clara, CA, 3am)
Winner D v Runner-up A (June 19, Foxborough, MA, 12am)
SEMI-FINALS
Winner of QF1 v Winner QF4 (June 22, Houston, TX, 2am)
Winner of QF2 v Winner QF3, (June 23, Chicago, IL, 1am)
FINAL
Winner SF1 v Winner SF 2 (June 27, East Rutherford, NJ, 1am)