Unai Emery makes two changes from their win against Arsenal, as Matty Cash and Douglas Luiz in for Diego Carlos and Morgan Rogers.
That’ll see Ezri Konsa shift back into his natural central position, as opposed to the full-back role he played at the Emirates.
Meanwhile, the hosts bring Yusuf Yazici into their attack, in their only change from their defeat from the first leg.
Lille XI: Chevalier, Tiago Santos, Diakite, Yoro, Ismaily, Andre, Bentaleb, Yazici, Haraldsson, Gudmundsson, David.
Subs: Mannone, Ngrel, Alexsandro, Gomes, Cabella, Ounas, Cavaleiro, Morais, Bouaddi, Toure, Ferrah.
Villa XI: Martinez, Cash, Konsa, Pau, Digne, Luiz, Tielemans, Diaby, Zaniolo, McGinn, Watkins.
Subs: Olsen, Gauci, Carlos, Lenglet, Duran, Rogers, Kelser-Hayden, Bailey, Iroegbunam, Munroe, Kellyman.
