Warning that drinking ANY amount of alcohol may raise risk of 60 diseases

Drinking alcohol increases your risk of developing 60 diseases, a major study suggests.

Liver cirrhosis — scarring caused by continuous, long-term liver damage — strokes and cancer are already well-established risks of excess boozing.

But Oxford University researchers, who analysed data from half a million men living in China, have now found it can raise the risk of gout and cataracts.

Other disorders never-before-linked to booze in the study include fractures, lung cancer and circulatory diseases.

Some of the links were apparent for low amounts of alcohol, even intake below NHS guidelines.

Experts said the findings show that drinking alcohol is liked to a ‘much wider range of diseases’ than previously thought. 

Researchers in the UK and Australia noted that while alcohol is responsible for ‘substantial disease’ around the world, their findings suggest it ‘may actually be beneficial’ for inflammation

Excessive alcohol consumption is estimated to be behind around 3million deaths worldwide each year. 

The NHS advises that men and women drink no more than 14 units of alcohol a week, with one unit being half a pint of beer or a small glass of wine.

But the World Health Organization (WHO) says that no amount of alcohol is safe. 

However, this is fiercely debated. Studies have suggested that a glass of wine or pint of beer a day can stave off a host of illnesses. 

Researchers from Oxford teamed up with academics at both Peking University and the Chinese Academy of Medical Sciences for the study.

How much alcohol is too much?

To keep health risks from alcohol to a low level, the NHS advises men and women not to regularly drink more than 14 units a week.

A unit of alcohol is 8g or 10ml of pure alcohol, which is about:

  • half a pint of lower to normal-strength lager/beer/cider (ABV 3.6%)
  • a single small shot measure (25ml) of spirits (25ml, ABV 40%)

A small glass (125ml, ABV 12%) of wine contains about 1.5 units of alcohol.

But the NHS warns the risk to your health is increased by drinking any amount of alcohol on a regular basis. 

Short-term risks include injury, violent behaviour and alcohol poisoning.

Long-term risks include heart and liver disease, strokes, as well as liver, bowel, moth and breast cancer.

People who drink as much as 14 units a week are advised to spread it evenly over three or more days, rather than binge drinking.

Women who are pregnant or trying to become pregnant are advised not to drink to reduce risks for the baby.

Source: NHS

They examined data from a Chinese database containing the health information of more than 512,000 adults, aged 52 on average. It included details on their drinking patterns.

About a third of men drank alcohol regularly — at least once a week — while the rate was just two per cent among women.

As a result, women were used as a control group to confirm that excess disease risk in men were caused by alcohol drinking, rather than a mechanism related to genetic variants.

They analysed hospital records of 12 years to assess how alcohol affected the risk of developing 207 different diseases. Some weren’t medical diseases as such, with transport accidents and injuries also included.

The findings, published in the journal Nature Medicine, show alcohol use increases the risks of 60 diseases in men in China.

This included 28 diseases previously established by the World Health Organization as alcohol-related, such as liver, bowel and rectal cancers. 

However, they also identified 33 not previously established, such as gout, cataract, some fractures and gastric ulcers.

Certain drinking patterns — such as drinking daily, binging or drinking outside mealtimes — particularly increased the risks of certain diseases, including liver cirrhosis.

The team also identified dose-dependent links, with every four drinks per day associated with a 14 per cent higher risk of having an alcohol-related disease.

Drinking this much alcohol also carried a six per cent increased risk of developing the 33 newly-identified alcohol-related diseases.

Additionally, every four drinks per day was linked with a more than two-fold higher risk of liver cirrhosis and gout.

Men who drank alcohol regularly had a higher risk of admission and of developing any diseases, compared to men who only drink occasionally. 

The study demonstrates the influence that alcohol intake may have on risk of disease in populations around the world, the team said. 

Pek Kei Im, study author, said: ‘Alcohol consumption is adversely related to a much wider range of diseases than has previously been established, and our findings show these associations are likely to be causal.’

Professor Liming Li, a senior author and CKB co-PI from Peking University, said: ‘Levels of alcohol consumption are rising in China, particularly among men. 

‘This large collaborative study demonstrates a need to strengthen alcohol control policies in China.’

Iona Millwood, associate professor at Oxford Population Health and a senior study author, said: ‘It is becoming clear that the harmful use of alcohol is one of the most important risk factors for poor health, both in China and globally.’

Fellow researcher Professor Zhengming Chen said: ‘This study provides important causal evidence of the scale of alcohol-related harms, which is critical to inform prevention strategies in different countries.’

THE 60 DISEASES ALCOHOL INCREASES THE RISK FOR

  1. Tuberculosis
  2. Laryngeal cancer
  3. Oesophageal cancer
  4. Liver cancer
  5. Uncertain neoplasm
  6. Colon cancer
  7. Lung cancer
  8. Rectal cancer
  9. Other cancer
  10. Lip, oral cavity and pharynx cancer
  11. Stomach cancer
  12. Other anaemias
  13. Purpura and other haemorrhagic conditions
  14. Other metabolic disorders
  15. Diabetes melitus
  16. Less common psychiatric and behavioural conditions combined
  17. Epilepsy
  18. Transient cerebral ischaemic attacks
  19. Cataract
  20. Phlebitis and thrombophlebitis
  21. Cardiomyopathy
  22. Intracerebral haemorrhage
  23. Sequelae of cerebrovascular disease
  24. Hypertensive heart disease
  25. Essential (primary) hypertension
  26. Cerebral infarction
  27. Complications of heart disease
  28. Stroke, not specified
  29. Occlusion and stenosis of cerebral arteries
  30. Occlusion and stenosis of precerebral arteries
  31. Other cerebrovascular diseases
  32. Chronic ischaemic heart disease
  33. Less common circulatory diseases combined
  34. Unspecified chronic bronchitis
  35. Other chronic obstructive pulmonary disease
  36. Pneumonia
  37. Alcoholic liver disease
  38. Fibrosis and cirrhosis of liver
  39. Other inflammatory liver diseases
  40. Abscess of anal and rectal regions
  41. Gastro−oesophageal reflux disease
  42. Gastric ulcer
  43. Other diseases of digestive system
  44. Other diseases of liver
  45. Pancreatitis
  46. Other local infections (skin/subcutaneous tissue)
  47. Osteonecrosis
  48. Gout
  49. Other arthrosis
  50. Abnormal results of function studies
  51. Malaise and fatigue
  52. Other ill−defined/unspecified mortality causes
  53. Unknown/unspecified morbidity causes
  54. Fracture of shoulder and upper arm
  55. Fracture of femur
  56. Fracture of rib(s)/sternum/thoracic spine
  57. Less common injury, poisoning and other external causes combined
  58. Intentional self−harm
  59. Falls
  60. Transport accidents

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